Concurrent Treatment for Substance Use Disorder and Trauma-Related Comorbidities: 2021 Update

Vu T, MacDougall D. (2021)

CADTH - N/A

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Evidence Categories

• Care setting: Community setting
• Population group: Adults
• Population group: Pre existing health condition
• Intervention: Supporting behaviour change
• Outcome: Changes to frequency/amount of alcohol use

Type of Evidence

Systematic Review

Aims

1. What is clinical effectiveness of concurrent treatment for patients with substance use disorders and comorbid post-traumatic stress disorder, anxiety, or depression?
2. What is the clinical effectiveness of the treatment of 1 condition for the improvement of all symptoms in patients with substance use disorder and comorbid post-traumatic stress disorder, anxiety, or depression?
3. What are the evidence-based guidelines regarding the treatment of patients with substance use disorders and comorbid post-traumatic stress disorder, anxiety, or depression?

Findings

Two systematic reviews and 8 randomized controlled trials were identified regarding the clinical effectiveness of concurrent treatment for patients with substance use disorders and comorbid post-traumatic stress disorder, anxiety, or depression. One systematic review and 2 non-randomized studies were identified regarding the clinical effectiveness of the treatment of 1 condition for the improvement of all symptoms in patients with substance use disorder and comorbid post-traumatic stress disorder, anxiety, or depression. Four evidence-based guidelines were identified regarding the treatment of patients with substance use disorders and comorbid post-traumatic stress disorder, anxiety, or depression.

Conclusions

Two systematic review , 8 randomised controlled trials and 2 non randomised studies were identified regarding the clinical effectiveness of concurrent treatment or the treatment of 1 condition for the improvement of all symptoms in patients with substance use disorder and comorbid post traumatic stress disorder, anxiety, or depression. Four evidence based guidelines were identified regarding the treatment of patients with substance use disorders and comorbid post traumatic stress disorder, anxiety or depression. No relevant HTAs were identified.