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NICE Underpinning Review
"Evidence assessing the effectiveness of pharmacological agents and/ or natural products in the treatment of self-harm is lacking, especially when compared with the evidence for psychosocial interventions. Whilst there has been an increase in the use of psychosocial interventions for self-harm, drug treatments are frequently used in clinical practice. The aim of this review is to assess the effects of pharmacological agents or natural products for self-harm compared to comparison types of treatment (for example, placebo or alternative pharmacological treatment) for people who have self-harmed."
"Recommendations supported by this evidence review This evidence review supports recommendation 1.11.10 - NG225"